产品简要
信息索取 :
公司名称 :
Toronto BioScience
产品类型 :
抗体
产品名称 :
Plasminogen activator inhibitor type-1 (human), rabbit polyclonal
目录 :
11070
规格 :
100微克
价格 :
181美元
克隆性 :
多克隆
宿主 :
反应物种 :
人类
应用 :
酶联免疫吸附测定
更多信息或购买 :
文章摘录数: 4
已发表的文献中的应用方法/种属/稀释度参考文献
Daniel A, Timmerman I, Kovacevic I, Hordijk P, Adriaanse L, Paatero I, et al. Plasminogen Activator Inhibitor-1 Controls Vascular Integrity by Regulating VE-Cadherin Trafficking. PLoS ONE. 2015;10:e0145684 pubmed 出版商
Marudamuthu A, Shetty S, Bhandary Y, Karandashova S, Thompson M, Sathish V, et al. Plasminogen activator inhibitor-1 suppresses profibrotic responses in fibroblasts from fibrotic lungs. J Biol Chem. 2015;290:9428-41 pubmed 出版商
Jacobs M. A review of the development of an ergonomically balanced chair. J Manipulative Physiol Ther. 1987;10:335-6 pubmed
Xu K, Liu X, Yang F, Cui D, Shi Y, Shen C, et al. PAI-1 -675 4G/5G polymorphism in association with diabetes and diabetic complications susceptibility: a meta-analysis study. PLoS ONE. 2013;8:e79150 pubmed 出版商
产品信息
目录代码 :
11070
产品名称 :
Plasminogen activator inhibitor type-1 (human), rabbit polyclonal
宿主物种 :
克隆性 :
多克隆
共轭 :
纯化
产品类型 :
抗体
规格 :
100微克
标价(美元) :
181美元
Pubmed号列表 :
26714278, 25648892, 24223897, 3437240
抗体亚型 :
兔IgG
产品描述 :
This rabbit polyclonal antibody can detect human plasminogen activator inhibitor type-1 (PAI-1) by ELISA.
物种摘要 :
人类特异性
背景 :
Plasminogen activator inhibitor-1 (PAI-1) is the primary inhibitor of tissue-type and urokinase-type plasminogen activator, playing a major role in fibrinolysis. PAI-1 is mainly produced by the endothelium, but is also secreted by other tissue types, such as adipose tissue. It is normally present at low levels in plasma and tissue, but its expression and release increased in various disease states (such as a number of forms of cancer), as well as in obesity and the metabolic syndrome. PAI-1 is also involved in the pathophysiology of renal, pulmonary, cardiovascular, and metabolic diseases. Elevated local or systemic PAI-1 can also exacerbate such pathologic conditions.
别名 :
纤溶酶原激活物抑制因子1(PAI-1), 又名PAI, PAI1, PLANH1, 和SERPINE1
免疫原 :
重组全长人类PAI-1在大肠杆菌中表达
特异性 :
人类
缓冲液 :
溶液在PBS
用途 :
ELISA - This antibody can be used in ELISA with the appropriate secondary reagents to detect human PAI-1
应用摘要 :
ELISA - This antibody can be used in ELISA with the appropriate secondary reagents to detect human PAI-1
储存 :
Store at –20°C. For long-term storage, aliquot and freeze at -70°C. Avoid repeated freeze/defrost cycles.
一般参考 :
1. Plasminogen activator inhibitor-1 (PAI-1): a key factor linking fibrinolysis and age-related subclinical and clinical conditions. Cesari M, Pahor M, Incalzi RA. Cardiovasc Ther. 2010 28(5):e72-91. 2. The plasminogen activation system: new targets in lung inflammation and remodeling. Schuliga M, Westall G, Xia Y, Stewart AG. Curr Opin Pharmacol. 2013 13(3):386-93
更多信息或购买 :
公司信息
Toronto BioScience
info@torontobioscience.com
www.torontobioscience.com
公司总部: 加拿大