产品简要
公司名称 :
Toronto BioScience
产品类型 :
抗体
产品名称 :
Phospho-Akt, rabbit polyclonal anti-Ser473
目录 :
11092
规格 :
100微克
价格 :
194美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
nonconjugated
反应物种 :
人类, 小鼠
应用 :
免疫印迹
更多信息或购买 :
产品信息
目录代码 :
11092
产品名称 :
Phospho-Akt, rabbit polyclonal anti-Ser473
宿主物种 :
兔
克隆性 :
多克隆
共轭 :
纯化
产品类型 :
抗体
规格 :
100微克
标价(美元) :
194美元
Pubmed号列表 :
7774014, 9005852, 9497382
抗体亚型 :
兔IgG
产品描述 :
This rabbit polyclonal antibody can detect human, mouse and rat phospho-Akt (Ser473) by western blot.
交叉活性 :
人类, 小鼠和大鼠
物种摘要 :
人类, 小鼠, &大鼠特异性
背景 :
Akt, also known as PKB or Rac, is a critical component of signaling pathways stimulated by various hormones and growth factors, such as insulin. Akt plays an important role in regulating cell metabolism and apoptosis. Akt is activated by phosphorylation at Thr308 by PDK1 and by phosphorylation at Ser473 by mammalian target of rapamycin (mTOR).
别名 :
Akt, is also known as AKT1, PKB, RAC, CWS6, PRKBA, PKB-ALPHA, and RAC-ALPHA
免疫原 :
Synthetic phosphopeptide corresponding to residues surrounding Ser473 of mouse Akt.
特异性 :
人类, 小鼠, 大鼠
缓冲液 :
溶液在PBS
用途 :
Western blot - This antibody can be used as primary antibody to detect phosphor-Akt (Ser473).
应用摘要 :
Western blot - This antibody can be used as primary antibody to detect phosphor-Akt (Ser473).
储存 :
Store at –20°C. For long-term storage, aliquot and freeze at -70°C. Avoid repeated freeze/defrost cycles.
一般参考 :
1. PI3K-PKB/Akt pathway. Hemmings BA, Restuccia DF. Cold Spring Harb Perspect Biol. 2012 4(9):a011189
2. Akt, FoxO and regulation of apoptosis. Zhang X, Tang N, Hadden TJ, Rishi AK. Biochim Biophys Acta. 2011 1813(11):1978-86
3. Akt signalling in health and disease. Hers I, Vincent EE, Tavaré JM. Cell Signal. 2011 Oct;23(10):1515-27.
更多信息或购买 :
公司信息
Toronto BioScience