产品简要
公司名称 :
Toronto BioScience
产品类型 :
抗体
产品名称 :
Plasminogen activator inhibitor type-1 (human), mouse monoclonal
目录 :
21070
规格 :
100微克
价格 :
220美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
3H3
反应物种 :
人类
更多信息或购买 :
文章摘录数: 4
参考文献
Daniel A, Timmerman I, Kovacevic I, Hordijk P, Adriaanse L, Paatero I, et al. Plasminogen Activator Inhibitor-1 Controls Vascular Integrity by Regulating VE-Cadherin Trafficking. PLoS ONE. 2015;10:e0145684 pubmed 出版商
Marudamuthu A, Shetty S, Bhandary Y, Karandashova S, Thompson M, Sathish V, et al. Plasminogen activator inhibitor-1 suppresses profibrotic responses in fibroblasts from fibrotic lungs. J Biol Chem. 2015;290:9428-41 pubmed 出版商
Xu K, Liu X, Yang F, Cui D, Shi Y, Shen C, et al. PAI-1 -675 4G/5G polymorphism in association with diabetes and diabetic complications susceptibility: a meta-analysis study. PLoS ONE. 2013;8:e79150 pubmed 出版商
Jacobs M. A review of the development of an ergonomically balanced chair. J Manipulative Physiol Ther. 1987;10:335-6 pubmed
产品信息
目录代码 :
21070
产品名称 :
Plasminogen activator inhibitor type-1 (human), mouse monoclonal
宿主物种 :
小鼠
克隆性 :
单克隆
共轭 :
纯化
产品类型 :
抗体
规格 :
100微克
标价(美元) :
220美元
Pubmed号列表 :
26714278, 25648892, 24223897, 3437240
克隆 :
3H3
抗体亚型 :
小鼠IgG
产品描述 :
This mouse monoclonal antibody can be used as a capture antibody in a human PAi-1 ELISA in combination with polyclonal anti-human PAI-1 antibody (Cat. No.: 11070)
物种摘要 :
人类特异性
背景 :
Plasminogen activator inhibitor-1 (PAI-1) is the primary inhibitor of tissue-type and urokinase-type plasminogen activator, playing a major role in fibrinolysis. PAI-1 is mainly produced by the endothelium, but is also secreted by other tissue types, such as adipose tissue. It is normally present at low levels in plasma and tissue, but its expression and release increased in various disease states (such as a number of forms of cancer), as well as in obesity and the metabolic syndrome. PAI-1 is also involved in the pathophysiology of renal, pulmonary, cardiovascular, and metabolic diseases. Elevated local or systemic PAI-1 can also exacerbate such pathologic conditions.
别名 :
纤溶酶原激活物抑制因子1(PAI-1), 又名PAI, PAI1, PLANH1, 和SERPINE1
免疫原 :
E. coli derived recombinant human PAI-1 (Cat. No. 41070)
特异性 :
人类
缓冲液 :
溶液在PBS
用途 :
ELISA - capture antibody
应用摘要 :
This antibody can be used as a capture antibody in a human PAi-1 ELISA in combination with polyclonal anti-human PAI-1 antibody (Cat. No.: 11070)
储存 :
存放在–20°C
一般参考 :
1. Plasminogen activator inhibitor-1 (PAI-1): a key factor linking fibrinolysis and age-related subclinical and clinical conditions. Cesari M, Pahor M, Incalzi RA. Cardiovasc Ther. 2010 28(5):e72-91. 2. The plasminogen activation system: new targets in lung inflammation and remodeling. Schuliga M, Westall G, Xia Y, Stewart AG. Curr Opin Pharmacol. 2013 13(3):386-93
更多信息或购买 :
公司信息
Toronto BioScience
info@torontobioscience.com
www.torontobioscience.com
公司总部: 加拿大