产品简要
公司名称 :
US Biological
产品类型 :
抗体
产品名称 :
CD40 (B Cell surface antigen CD40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5)
目录 :
030056
规格 :
100微升
价格 :
473美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
13B134
反应物种 :
人类
更多信息或购买 :
产品信息
目录号 :
030056
Product wo Prefix :
CD40 (B Cell surface antigen CD40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5)
宿主 :
小鼠
产品类型 :
单克隆抗体
类别 :
抗体
尺寸1 :
100微升
Size1 List :
473美元
克隆#USB :
13B134
抗体亚型 :
IgG1
Desc1 :
CD40 molecule, TNF receptor superfamily member 5. It is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. Applications: Immunofluorescence: 1:200-1:1000. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Hu
又名 :
p50;Bp50;CDW40;TNFRSF5
免疫原 :
Purified recombinant fragment of CD40 expressed in E. coli.
特异性 :
人类
纯度 :
腹水
形式 :
Ascites fluid, 0.03% sodium azide.
浓度 :
未确定
Desc2 :
Product Type: Mab Isotype: IgG1 Clone No: 13B134 Host: mouse Source: human Concentration: Not determined Form: Ascites fluid, 0.03% sodium azide. Purity: Ascites Immunogen: Purified recombinant fragment of CD40 expressed in E. coli. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E
储存温度 :
-20°C
参考文献 :
1. Clin Cancer Res. 2003 Feb;9(2):722-8. 2. Clin Cancer Res. 2003 Feb;9(2):619-24. 3. Immunity. 1999 Sep;11(3):339-48.
更多信息或购买 :
公司信息
US Biological
4 Technology Way
Salem, MA01970
tech@usbio.net
https://www.usbio.net
800-520-3011 781-639-5092
公司总部: 美国
United States Biological是生命科学领域的知名品牌,致力于用真实、有价值的个性化采购经验降低研究用成本。