CD45(蛋白酪氨酸磷酸酶 , 受体类型, C, 蛋白酪氨酸磷酸酶受体C, LCA, 白细胞共同抗原, LY5, 受体类型酪氨酸蛋白磷酸酶C, T200)

产品简要

公司名称 :

US Biological

产品类型 :

抗体

产品名称 :

CD45(蛋白酪氨酸磷酸酶 , 受体类型, C, 蛋白酪氨酸磷酸酶受体C, LCA, 白细胞共同抗原, LY5, 受体类型酪氨酸蛋白磷酸酶C, T200)

030058

规格 :

100微升

价格 :

473美元

克隆性 :

单克隆

宿主 :

小鼠

共轭标签 :

未共轭

克隆名称 :

13B136

反应物种 :

人类

更多信息或购买 :

US Biological 产品网页

产品信息

目录号 :

030058

Product wo Prefix :

CD45(蛋白酪氨酸磷酸酶 , 受体类型, C, 蛋白酪氨酸磷酸酶受体C, LCA, 白细胞共同抗原, LY5, 受体类型酪氨酸蛋白磷酸酶C, T200)

宿主 :

小鼠

产品类型 :

单克隆抗体

类别 :

抗体

尺寸1 :

100微升

Size1 List :

473美元

克隆#USB :

13B136

抗体亚型 :

IgG1

Desc1 :

CD45, also known as TPRC(protein tyrosine phosphatase, receptor type, C). The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. Applications: Western Bloting: 1:500-1:2000. Immunohistochemistry: 1:200-1:1000. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

又名 :

LCA;LY5;B220;CD45;T200;CD45R;GP180;蛋白酪氨酸磷酸酶受体C

免疫原 :

Purified recombinant fragment of CD45 expressed in E. coli.

特异性 :

人类

纯度 :

腹水

形式 :

Ascites fluid, 0.03% sodium azide.

浓度 :

未确定

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 13B136 Host: mouse Source: human Concentration: Not determined Form: Ascites fluid, 0.03% sodium azide. Purity: Ascites Immunogen: Purified recombinant fragment of CD45 expressed in E. coli. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E免疫组化免疫印迹

储存温度 :

-20°C

参考文献 :

1. Biol Chem. 2008 May;389(5):561-8. 2. Immunology. 2008 Dec;125(4):558-69.

更多信息或购买 :

US Biological 产品网页

公司信息