CDKN1B (CDKN4, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, KIP1)

产品简要

公司名称 :

US Biological

产品类型 :

抗体

产品名称 :

CDKN1B (CDKN4, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, KIP1)

030083

规格 :

100微升

价格 :

473美元

克隆性 :

单克隆

宿主 :

小鼠

共轭标签 :

未共轭

克隆名称 :

13B161

反应物种 :

人类

更多信息或购买 :

US Biological 产品网页

产品信息

目录号 :

030083

Product wo Prefix :

CDKN1B (CDKN4, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, KIP1)

宿主 :

小鼠

产品类型 :

单克隆抗体

类别 :

抗体

尺寸1 :

100微升

Size1 List :

473美元

克隆#USB :

13B161

抗体亚型 :

IgG1

Desc1 :

p27 KIP 1 is a cell cycle regulatory mitotic inhibitor of cdk activity. p27 KIP 1 is a candidate tumor suppressor gene, and has been proposed to function as a possible mediator of TGF beta induced G1 arrest. p27 KIP 1 is up regulated in response to antimitogenic stimuli. The increased protein expression of p27 results in cellular arrest by binding to cyclin/Cdk complexes such as cyclin D1/Cdk4. Decreased levels of p27Kip1, mainly due to proteosomal degradation, are found in various epithelial tumors originating from lung, breast, colon, ovary, esophagus, thyroid and prostate.Tissue specificity: Expressed in all tissues tested. Highest levels in skeletal muscle, lowest in liver and kidney. Applications: Western Bloting: 1:500-1:2000. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

又名 :

KIP1;MEN4;CDKN4;MEN1B;P27KIP1;CDKN1B

免疫原 :

纯化重组片段对应于人CDKN1B在大肠杆菌中表达

特异性 :

人类

纯度 :

腹水

形式 :

Ascites fluid, 0.03% sodium azide.

浓度 :

未确定

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 13B161 Host: mouse Source: human Concentration: Not determined Form: Ascites fluid, 0.03% sodium azide. Purity: Ascites Immunogen: Purified recombinant fragment of human CDKN1B expressed in E. coli. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E免疫印迹

储存温度 :

-20°C

参考文献 :

1. Exp Mol Med. 2009 Nov 30;41(11):765-71. 2. Int J Gynecol Pathol. 2010 Jan;29(1):8-18.

更多信息或购买 :

US Biological 产品网页

公司信息