抗体

CHD3 (Chromodomain-helicase-DNA-binding protein 3)

030093

100微升

473美元

单克隆

小鼠

未共轭

13B171

CHD3 (Chromodomain-helicase-DNA-binding protein 3)

小鼠

单克隆抗体

抗体

100微升

473美元

13B171

IgG1

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. Applications: Western Bloting: 1:500-1:2000. Immunohistochemistry: 1:200-1:1000. Immunofluorescence: 1:200-1:1000. Flow cytometry: 1:200-1:400. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu Mo

ZFH; Mi-2a; Mi2-ALPHA; CHD3

纯化重组片段对应于人CHD3在大肠杆菌中表达

人类, 小鼠

腹水

Ascites fluid, 0.03% sodium azide.

未确定

Product Type: Mab Isotype: IgG1 Clone No: 13B171 Host: mouse Source: human Concentration: Not determined Form: Ascites fluid, 0.03% sodium azide. Purity: Ascites Immunogen: Purified recombinant fragment of human CHD3 expressed in E. coli. Specificity: Human, Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E FC免疫组化免疫印迹

-20°C

1. Virus Res. 2003 Dec;98(1):83-91. 2. Mol Cell. 2004 Sep 24;15(6):853-65. 3. J Biol Chem. 2008 Dec 12;283(50):34976-82.