ER甲 | US Biological 030186 产品信息

产品简要

公司名称 :

US Biological

产品类型 :

抗体

产品名称 :

ER甲

030186

规格 :

100微升

价格 :

380美元

克隆性 :

单克隆

宿主 :

小鼠

共轭标签 :

未共轭

克隆名称 :

13B264

反应物种 :

人类

更多信息或购买 :

US Biological 产品网页

产品信息

目录号 :

030186

Product wo Prefix :

ER甲

宿主 :

小鼠

产品类型 :

单克隆抗体

类别 :

抗体

尺寸1 :

100微升

Size1 List :

380美元

克隆#USB :

13B264

抗体亚型 :

IgG1

Desc1 :

The estrogen receptor (ER) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Alternative splicing results in several ER mRNA transcripts, which differ primarily in their 5-prime untranslated regions. Two isoforms of the human ER, ERA and ER-beta, occur, each with distinct tissue and cell patterns of expression. Pelletier and El-Alfy (2000) studied the immunocytochemical localization of ESRA and ESRB in human reproductive tissues. In the ovary, ERB immunoreactivity was found in nuclei of granulosa cells of growing follicles at all stages from primary to mature follicles, interstitial gland, and germinal epithelium cells. Nuclear staining for ERA occurred in thecal, interstitial gland, and germinal epithelium cells. In the uterus, strong ERA immunoreactivity was detected in nuclei of epithelial, stromal, and muscle cells. Applications: Western Bloting: 1:500-1:2000. Immunohistochemistry: 1:200-1:1000. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

又名 :

ER; ESR1; Era; ESRA

免疫原 :

纯化重组片段对应于人ER甲(410-592aa)在大肠杆菌中表达

特异性 :

人类

纯度 :

纯化

形式 :

纯化抗体在PBS, 0.03% 叠氮化钠

浓度 :

~1毫克/毫升

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 13B264 Host: mouse Source: human Concentration: ~1mg/ml Form: Purified antibody in PBS, 0.03% sodium azide. Purity: Purified Immunogen: Purified recombinant fragment of human ER-alpha (410-592aa) expressed in E. coli. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E免疫组化免疫印迹

储存温度 :

-20°C

参考文献 :

1. Paech K. Science 1997, 277: 1508- 10. 2. Pertschuk LP，Cancer, 1996. 199677: 514- 9.

更多信息或购买 :

US Biological 产品网页

公司信息