缺氧诱导因子1A | US Biological 030298 产品信息

产品简要

公司名称 :

US Biological

产品类型 :

抗体

产品名称 :

缺氧诱导因子1A

030298

规格 :

100微升

价格 :

502美元

克隆性 :

单克隆

宿主 :

小鼠

共轭标签 :

未共轭

克隆名称 :

13B376

反应物种 :

人类

更多信息或购买 :

US Biological 产品网页

产品信息

目录号 :

030298

Product wo Prefix :

缺氧诱导因子1A

宿主 :

小鼠

产品类型 :

单克隆抗体

类别 :

抗体

尺寸1 :

100微升

Size1 List :

502美元

克隆#USB :

13B376

抗体亚型 :

IgG1

Desc1 :

Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. (provided by RefSeq) Tissue specificity: Expressed in most tissues with highest levels in kidney and heart. Overexpressed in the majority of common human cancers and their metastases, due to the presence of intratumoral hypoxia and as a result of mutations in genes encoding oncoproteins and tumor suppressors. Applications: Western Bloting: 1:500-1:2000. Immunohistochemistry: 1:200-1:1000. Immunofluorescence: 1:200-1:1000. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mk Mo

又名 :

HIF1;MOP1;PASD8;bHLHe78;HIF-1alpha;HIF1-甲;缺氧诱导因子1A

免疫原 :

纯化重组片段对应于人缺氧诱导因子1A在大肠杆菌中表达

特异性 :

Human, Mouse, Monkey

纯度 :

腹水

形式 :

Ascites fluid, 0.03% sodium azide.

浓度 :

未确定

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 13B376 Host: mouse Source: human Concentration: Not determined Form: Ascites fluid, 0.03% sodium azide. Purity: Ascites Immunogen: Purified recombinant fragment of human HIF1A expressed in E. coli. Specificity: Human, Mouse, Monkey Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E免疫组化免疫印迹

储存温度 :

-20°C

参考文献 :

1. Int J Radiat Oncol Biol Phys. 2008 Dec 1;72(5):1551-9. 2. Eur J Appl Physiol. 2009 Mar;105(4):515-24.

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