抗体

细胞间粘附分子1(细胞间粘附分子1, ICAM-1)

030314

100微升

473美元

单克隆

小鼠

未共轭

13B392

细胞间粘附分子1(细胞间粘附分子1, ICAM-1)

小鼠

单克隆抗体

抗体

100微升

473美元

13B392

IgG1

ICAM1 is a 85-110kD single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils), with lower levels that increase in inflammation. ICAM1 is also detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria. Applications: Western Bloting: 1:500-1:2000. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

BB2;CD54;P3.58;细胞间粘附分子1

纯化重组片段对应于人细胞间粘附分子1(28-480aa)在大肠杆菌中表达

人类

腹水

Ascites fluid, 0.03% sodium azide.

未确定

Product Type: Mab Isotype: IgG1 Clone No: 13B392 Host: mouse Source: human Concentration: Not determined Form: Ascites fluid, 0.03% sodium azide. Purity: Ascites Immunogen: Purified recombinant fragment of human ICAM1(28-480aa) expressed in E. coli. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫印迹

-20°C

1. J Neurosci Res. 1992 Feb;31(2):365-74. 2. J Cell Biol. 2002 Jun 24;157(7):1233-45. 3. J Hepatol. 2004 Mar;40(3):375-9.