抗体

JAK3 (Janus kinase 3)

030355

100微升

436美元

单克隆

小鼠

未共轭

13B433

JAK3 (Janus kinase 3)

小鼠

单克隆抗体

抗体

100微升

436美元

13B433

IgG1

JAK3, Janus kinase 3. It is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). Applications: Suitable for use in Immunofluorescence, Flow Cytometry, ELISA, Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:100-1:500. Immunofluorescence: 1:200-1:1000. Flow Cytometry: 1:200-1:400. ELISA: 1:10,000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu Mo

JAKL;LJAK

纯化重组片段对应于人JAK3, aa116-328, 在大肠杆菌中表达

Recognizes human JAK3. Species Crossreactivity: mouse

腹水

Supplied as a liquid in 0.03% sodium azide.

未确定

Product Type: Mab Isotype: IgG1 Clone No: 13B433 Host: mouse Source: human Concentration: Not determined Form: Supplied as a liquid in 0.03% sodium azide. Purity: Ascites Immunogen: Purified recombinant fragment of human JAK3, aa116-328, expressed in E. coli. Specificity: Recognizes human JAK3. Species Crossreactivity: mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E FC IF免疫印迹

-20°C

1. J Biol Chem. 1995 Oct 20;270(42):25028-36. 2. Proc Natl Acad Sci U S A. 1994 Jul 5;91(14):6374-8. 3. Leuk Lymphoma. 2002 Dec;43(12):2355-62.