抗体

KIT

030370

100微升

502美元

单克隆

小鼠

未共轭

13B448

KIT

小鼠

单克隆抗体

抗体

100微升

502美元

13B448

IgG1

The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell prolif- eration, apoptosis and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto- oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications have not been tested. Recommended Dilutions: Western Blot: 1:500-1:2000. Immunohistochemistry: 1:200-1:1000. ELISA: 1:10,000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

PBT;SCFR;C-kit;CD117

Purified recombinant protein fragment of human KIT expressed in E. coli.

识别人类KIT

腹水

Supplied as a liquid 0.03% sodium azide.

未确定

Product Type: Mab Isotype: IgG1 Clone No: 13B448 Host: mouse Source: human Concentration: Not determined Form: Supplied as a liquid 0.03% sodium azide. Purity: Ascites Immunogen: Purified recombinant protein fragment of human KIT expressed in E. coli. Specificity: Recognizes human KIT Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫组化免疫印迹

-20°C

1. Curr Hematol Malig Rep. 2009 Apr;4(2):77-82. 2. Georgian Med News. 2010 Mar;(180):13-9

https://usbio-images.r.worldssl.net/prodimages/11/030370_1.jpg

Immunohistochemical analysis of paraffin-embedded gastrointestinal stromal tumor using 030370 with DAB staining.