LMNA(核纤层蛋白A/C) | US Biological 030398 产品信息

产品简要

公司名称 :

US Biological

产品类型 :

抗体

产品名称 :

LMNA(核纤层蛋白A/C)

030398

规格 :

100微升

价格 :

502美元

克隆性 :

单克隆

宿主 :

小鼠

共轭标签 :

未共轭

克隆名称 :

13B476

反应物种 :

人类

更多信息或购买 :

US Biological 产品网页

产品信息

目录号 :

030398

Product wo Prefix :

LMNA(核纤层蛋白A/C)

宿主 :

小鼠

产品类型 :

单克隆抗体

类别 :

抗体

尺寸1 :

100微升

Size1 List :

502美元

克隆#USB :

13B476

抗体亚型 :

IgG1

Desc1 :

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. Applications: Western Bloting: 1:500-1:2000. Immunohistochemistry: 1:200-1:1000. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mo Rt

又名 :

FPL;IDC;LFP;CDDC;EMD2;FPLD;HGPS;LDP1;LMN1;LMNC;PRO1;CDCD1;CMD1A;FPLD2;LMNL1;CMT2B1

免疫原 :

纯化重组片段对应于人LMNA在大肠杆菌中表达

特异性 :

人类, 小鼠, 大鼠

纯度 :

腹水

形式 :

Ascites fluid, 0.03% sodium azide.

浓度 :

未确定

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 13B476 Host: mouse Source: human Concentration: Not determined Form: Ascites fluid, 0.03% sodium azide. Purity: Ascites Immunogen: Purified recombinant fragment of human LMNA expressed in E. coli. Specificity: Human, Mouse, Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E免疫组化免疫印迹

储存温度 :

-20°C

参考文献 :

1. Muscle Nerve. 2010 Jan;41(1):85-91. 2. Endocrine. 2009 Dec;36(3):518-23.

更多信息或购买 :

US Biological 产品网页

公司信息