抗体

MCP-1 (Monocyte chemotactic protein 1, CCL2)

030437

100微升

436美元

单克隆

小鼠

未共轭

13B515

MCP-1 (Monocyte chemotactic protein 1, CCL2)

小鼠

单克隆抗体

抗体

100微升

436美元

13B515

IgG1, k

Monocyte chemoattractant protein-1 (MCP-1) is a member of the chemokine-beta family of cytokines. The protein is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. It may play a inprotant role in the initiation and/or progression of pulmonary hypertension (PH). Blockade of a systemic MCP-1 signal pathway in vivo may prevent PH. Applications: Western Bloting: 1:500-1:2000. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

MCP1

纯化重组片段对应于人MCP-1在大肠杆菌中表达

人类

纯化

纯化抗体在PBS, 0.03% 叠氮化钠

~1毫克/毫升

Product Type: Mab Isotype: IgG1,k Clone No: 13B515 Host: mouse Source: human Concentration: ~1mg/ml Form: Purified antibody in PBS, 0.03% sodium azide. Purity: Purified Immunogen: Purified recombinant fragment of human MCP-1 expressed in E. coli. Specificity: human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫印迹

-20°C

1. Yoshimura T. et al. 1989. FEBS Lett. 244:487-493. 2. Yoshimura T. et al. 1991. Adv. Exp. Med. Biol. 305:47-56. 3. Rollins B.J. et al. 1991. Genomics. 10:489-492.