NEFH (Neurofilament Heavy Polypeptide, NF-H, 200kD Neurofilament Protein, Neurofilament Triplet H Protein, KIAA0845, NFH)

产品简要

公司名称 :

US Biological

产品类型 :

抗体

产品名称 :

NEFH (Neurofilament Heavy Polypeptide, NF-H, 200kD Neurofilament Protein, Neurofilament Triplet H Protein, KIAA0845, NFH)

030483

规格 :

100微克

价格 :

502美元

克隆性 :

单克隆

宿主 :

小鼠

共轭标签 :

未共轭

克隆名称 :

13B561

反应物种 :

人类

更多信息或购买 :

US Biological 产品网页

产品信息

目录号 :

030483

Product wo Prefix :

NEFH (Neurofilament Heavy Polypeptide, NF-H, 200kD Neurofilament Protein, Neurofilament Triplet H Protein, KIAA0845, NFH)

宿主 :

小鼠

产品类型 :

单克隆抗体

类别 :

抗体

尺寸1 :

100微克

Size1 List :

502美元

克隆#USB :

13B561

抗体亚型 :

IgG1

Desc1 :

Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglian cells. Neurofilaments consist of three major subunits with molecular weights of 68kD, 160kD and 200kD. This antibody will help detect the neurofilament 200kD subunit in normal and uncharacterized tissues. Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. Applications: Western Blot: 1:500-1:2000 Immunohistochemistry: 1:200-1:1000 ELISA: 1:10000 proposed Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

免疫原 :

纯化重组片段对应于人NEFH(AA: 968-1020)在大肠杆菌中表达

特异性 :

人类

纯度 :

纯化

形式 :

Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer

浓度 :

As reported

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 13B561 Host: mouse Source: human Concentration: As reported Form: Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer Purity: Purified Immunogen: Purified recombinant fragment of human NEFH (AA: 968-1020) expressed in E. coli. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E免疫组化免疫印迹

储存温度 :

-20°C

参考文献 :

1.J Neurol Sci. 2011 May 15;304(1-2):117-21. 2.Neurochem Res. 2011 Dec;36(12):2287-91.

更多信息或购买 :

US Biological 产品网页

公司信息