抗体

Osteopontin (Bone Sialoprotein 1, SPP-1, Urinary Stone Protein, Uropontin, Nephropontin, Secreted Phosphoprotein 1, SPP1, BNSP, OPN, PSEC0156, ETA-1)

030512

100微克

502美元

单克隆

小鼠

未共轭

13B590

Osteopontin (Bone Sialoprotein 1, SPP-1, Urinary Stone Protein, Uropontin, Nephropontin, Secreted Phosphoprotein 1, SPP1, BNSP, OPN, PSEC0156, ETA-1)

小鼠

单克隆抗体

抗体

100微克

502美元

13B590

IgG1

The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. Osteopontin, also named early T lymphocyte activation protein 1, secreted phosphoprotein, and bone sialoprotein 1, is a secreted acidic phosphorylated glycoprotein originally isolated from bone matrix. It has been shown to bind to different cell types through interactions with various integrins and CD44 variants. It has important functions in bone metabolism and inflammatory processes. Applications: Western Blot: 1:500-1:2000 Immunohistochemistry: 1:200-1:1000 Immunocytochemistry: 1:200-1:1000 ELISA: 1:10000 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

纯化重组片段对应于人SPP1(AA: 167-314)在大肠杆菌中表达

人类

纯化

Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer

As reported

Product Type: Mab Isotype: IgG1 Clone No: 13B590 Host: mouse Source: human Concentration: As reported Form: Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer Purity: Purified Immunogen: Purified recombinant fragment of human SPP1 (AA: 167-314) expressed in E. coli. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E细胞化学免疫组化免疫印迹

-20°C

1.Blood. 2012 May 31;119(22):5215-20. 2.J Cancer Res Ther. 2011 Apr-Jun;7(2):138-42.