产品简要
公司名称 :
US Biological
产品类型 :
抗体
产品名称 :
PAX8 (Paired box protein Pax-8)
目录 :
030531
规格 :
100微升
价格 :
473美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
13B609
反应物种 :
人类
更多信息或购买 :
产品信息
目录号 :
030531
Product wo Prefix :
PAX8 (Paired box protein Pax-8)
宿主 :
小鼠
产品类型 :
单克隆抗体
类别 :
抗体
尺寸1 :
100微升
Size1 List :
473美元
克隆#USB :
13B609
抗体亚型 :
IgG1
Desc1 :
This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas.Tissue specificity: Expressed in the excretory system, thyroid gland and Wilms tumors.ABCAM: This protein is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain, an octapeptide, and a paired-type homeodomain. This family plays critical roles during fetal development and cancer growth. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Alternative splicing in the gene by inclusion or exclusion of exons 7 and/or 8 has produced several known products but the biological significance of the variants is unknown. Several other splice variants have been proposed but the full nature of these products has not been described. Pax8 is also a marker of otic progenitor cells. Applications: Western Bloting: 1:500-1:2000. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Hu
又名 :
PAX8
免疫原 :
纯化重组片段对应于人PAX8在大肠杆菌中表达
特异性 :
人类
纯度 :
腹水
形式 :
Ascites fluid, 0.03% sodium azide.
浓度 :
未确定
Desc2 :
Product Type: Mab Isotype: IgG1 Clone No: 13B609 Host: mouse Source: human Concentration: Not determined Form: Ascites fluid, 0.03% sodium azide. Purity: Ascites Immunogen: Purified recombinant fragment of human PAX8 expressed in E. coli. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E免疫印迹
储存温度 :
-20°C
参考文献 :
1. Thyroid. 2009 Jan;19(1):61-8. 2. Cancer Genet Cytogenet. 2010 Jan 1;196(1):7-13. 3. Cancer Cytopathol. 2010 Oct 25;118(5):298-302.
更多信息或购买 :
公司信息
US Biological
4 Technology Way
Salem, MA01970
tech@usbio.net
https://www.usbio.net
800-520-3011 781-639-5092
公司总部: 美国
United States Biological是生命科学领域的知名品牌,致力于用真实、有价值的个性化采购经验降低研究用成本。