PDGFRb (Platelet-derived growth factor receptor, beta polypeptide)

产品简要

公司名称 :

US Biological

产品类型 :

抗体

产品名称 :

PDGFRb (Platelet-derived growth factor receptor, beta polypeptide)

030534

规格 :

100微升

价格 :

473美元

克隆性 :

单克隆

宿主 :

小鼠

共轭标签 :

未共轭

克隆名称 :

13B612

反应物种 :

人类

更多信息或购买 :

US Biological 产品网页

产品信息

目录号 :

030534

Product wo Prefix :

PDGFRb (Platelet-derived growth factor receptor, beta polypeptide)

宿主 :

小鼠

产品类型 :

单克隆抗体

类别 :

抗体

尺寸1 :

100微升

Size1 List :

473美元

克隆#USB :

13B612

抗体亚型 :

IgG1

Desc1 :

Platelet-derived growth factor receptor, beta polypeptide, also known as PDGFRB, PDGFRβ or CD140B. It is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. This family exist as several disulphide-bonded, dimeric isoforms (PDGF AA, PDGF AB, PDGF BB, PDGF CC and PDGF DD) that bind in a specific pattern to two closely related receptor tyrosine kinases, PDGF receptor α (PDGFRα) and PDGF receptor β (PDGFRβ). These growth factors are mitogens for cells of mesenchymal origin. PDGFRB is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. Applications: Western Bloting: 1:500-1:2000. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mo

又名 :

JTK12;PDGFR;CD140B;血小板衍生的生长因子受体1;血小板衍生的生长因子受体b

免疫原 :

纯化重组片段对应于人PDGFRβ在大肠杆菌中表达

特异性 :

人类, 小鼠

纯度 :

腹水

形式 :

Ascites fluid, 0.03% sodium azide.

浓度 :

未确定

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 13B612 Host: mouse Source: human Concentration: Not determined Form: Ascites fluid, 0.03% sodium azide. Purity: Ascites Immunogen: Purified recombinant fragment of human PDGFRβ expressed in E. coli. Specificity: Human, Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E免疫印迹

储存温度 :

-20°C

参考文献 :

1. Biochem Biophys Res Commun. 1997 Jun 27;235(3):455-60. 2. Hum Pathol. 2005 Mar;36(3):242-9. 3. J Virol. 2007 May;81(10):5112-20.

更多信息或购买 :

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公司信息