抗体

PSAP (Cerebroside sulfate activator, FLJ00245, GLBA, MGC110993, Prosaposin, SAP1)

030572

100微克

502美元

单克隆

小鼠

未共轭

13B650

PSAP (Cerebroside sulfate activator, FLJ00245, GLBA, MGC110993, Prosaposin, SAP1)

小鼠

单克隆抗体

抗体

100微克

502美元

13B650

IgG1

This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. Applications: Western Blot: 1:500-1:2000 Immunohistochemistry: 1:200-1:1000 Immunocytochemistry: 1:50-1:500 Flow Cytometry: 1:200-1:400 ELISA: 1:10000 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

纯化重组片段对应于人PSAP(AA: 325-524)在大肠杆菌中表达

人类

纯化

Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer

As reported

Product Type: Mab Isotype: IgG1 Clone No: 13B650 Host: mouse Source: human Concentration: As reported Form: Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer Purity: Purified Immunogen: Purified recombinant fragment of human PSAP (AA: 325-524 ) expressed in E. coli. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E FC细胞化学免疫组化免疫印迹

-20°C

1.Biochem J. 2012 Jan 15;441(2):665-74. 2.Mol Cancer. 2010 Feb 4;9:30.