产品简要
公司名称 :
US Biological
产品类型 :
抗体
产品名称 :
PTPN11
目录 :
030580
规格 :
100微升
价格 :
502美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
13B658
反应物种 :
人类
更多信息或购买 :
产品信息
目录号 :
030580
Product wo Prefix :
PTPN11
宿主 :
小鼠
产品类型 :
单克隆抗体
类别 :
抗体
尺寸1 :
100微升
Size1 List :
502美元
克隆#USB :
13B658
抗体亚型 :
IgG1
Desc1 :
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. Applications: Western Blot: 1:500-1:2000 Immunohistochemistry: 1:200-1:1000 Immunocytochemistry: 1:200-1:1000 Flow Cytometry: 1:200-1:400 ELISA: 1:10000 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Hu
又名 :
CFC;NS1;SHP2;BPTP3;PTP2C;PTP-1D;SH-PTP2;SH-PTP3;MGC14433
免疫原 :
纯化重组片段对应于人PTPN11(AA: 263-329)在大肠杆菌中表达
特异性 :
人类
纯度 :
纯化
形式 :
Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer
浓度 :
~1毫克/毫升
Desc2 :
Product Type: Mab Isotype: IgG1 Clone No: 13B658 Host: mouse Source: human Concentration: ~1mg/ml Form: Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer Purity: Purified Immunogen: Purified recombinant fragment of human PTPN11 (AA: 263-329) expressed in E. coli. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E FC细胞化学免疫组化免疫印迹
储存温度 :
-20°C
参考文献 :
1.Blood. 2011 Aug 11;118(6):1504-15. 2.Cancer Cell. 2011 May 17;19(5):629-39.
更多信息或购买 :
公司信息
US Biological
4 Technology Way
Salem, MA01970
tech@usbio.net
https://www.usbio.net
800-520-3011 781-639-5092
公司总部: 美国
United States Biological是生命科学领域的知名品牌,致力于用真实、有价值的个性化采购经验降低研究用成本。