产品简要
公司名称 :
US Biological
产品类型 :
抗体
产品名称 :
RAF1
目录 :
030588
规格 :
100微升
价格 :
502美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
13B666
反应物种 :
人类
更多信息或购买 :
产品信息
目录号 :
030588
Product wo Prefix :
RAF1
宿主 :
小鼠
产品类型 :
单克隆抗体
类别 :
抗体
尺寸1 :
100微升
Size1 List :
502美元
克隆#USB :
13B666
抗体亚型 :
IgG1
Desc1 :
This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. Applications: Western Bloting: 1:500-1:2000. Immunohistochemistry: 1:200-1:1000. Flow cytometry: 1:200-1:400. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Hu
又名 :
NS5; CRAF; Raf-1; c-Raf
免疫原 :
纯化重组片段对应于人RAF1在大肠杆菌中表达
特异性 :
人类
纯度 :
纯化
形式 :
Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer.
浓度 :
~1毫克/毫升
Desc2 :
Product Type: Mab Isotype: IgG1 Clone No: 13B666 Host: mouse Source: human Concentration: ~1mg/ml Form: Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer. Purity: Purified Immunogen: Purified recombinant fragment of human RAF1 expressed in E. coli. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E FC免疫组化免疫印迹
储存温度 :
-20°C
参考文献 :
1. Am J Hum Genet. 2009 Nov;85(5):628-42. 2. Mol Cancer Res. 2009 Oct;7(10):1635-44.
更多信息或购买 :
公司信息
US Biological
4 Technology Way
Salem, MA01970
tech@usbio.net
https://www.usbio.net
800-520-3011 781-639-5092
公司总部: 美国
United States Biological是生命科学领域的知名品牌,致力于用真实、有价值的个性化采购经验降低研究用成本。