抗体

RB (retinoblastoma 1, Retinoblastoma-associated protein)

030594

100微升

362美元

单克隆

小鼠

未共轭

13B672

RB (retinoblastoma 1, Retinoblastoma-associated protein)

小鼠

单克隆抗体

抗体

100微升

362美元

13B672

IgG1

The Rb protein regulates differentiation, apoptosis, and cell cycle control by coordinating the cell cycle at G1-S with transcriptional machinery. During G1, cyclin D-dependent kinase-mediated phosphorylation of Rb at Ser-795 marks the conversion of Rb from a transcriptionally repressive hypophosphorylated state to an inactive, phosphorylated state, which may be sustained through mitosis by differential phosphorylation of up to 16 putative serine or threonine residues Pediatric cancer retinoblastoma and the formation of other human tumors can be attributed to mutations in the retinoblastoma tumor suppressor gene (Rb). Applications: Suitable for use in ELISA ans Immunohistochemistry. Other applications not tested. Recommended Dilutions: ELISA: 1:10,000 Immunohistochemistry: 1:200-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

RB; pRb; OSRC; pp110; p105-Rb; RB1

纯化重组片段对应于人RB在大肠杆菌中表达

识别人类RB

腹水

Supplied as a liquid, 0.03% sodium azide

未确定

Product Type: Mab Isotype: IgG1 Clone No: 13B672 Host: mouse Source: human Concentration: Not Determined Form: Supplied as a liquid, 0.03% sodium azide Purity: Ascites Immunogen: Purified recombinant fragment of human RB expressed in E. coli. Specificity: Recognizes human RB. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫组化

-20°C

1。 癌基因19:562-570。 2。 细胞81:323-330

https://usbio-images.r.worldssl.net/prodimages/3/030594_1.jpg