抗体

SNCG (breast cancer-specific protein 1)

030640

100微升

436美元

单克隆

小鼠

未共轭

13B718

SNCG (breast cancer-specific protein 1)

小鼠

单克隆抗体

抗体

100微升

436美元

13B718

IgG1

SNCG(also designated gamma-synuclein or breast cancer-specific protein 1),with 127-amino acid protein(about 14kD), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development. Applications: Western Bloting: 1:500-1:2000. Immunohistochemistry: 1:200-1:1000. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

SR;BCSG1

Purified recombinant fragment of SNCG expressed in E. coli.

人类

纯化

纯化抗体在PBS, 0.03% 叠氮化钠

~1毫克/毫升

Product Type: Mab Isotype: IgG1 Clone No: 13B718 Host: mouse Source: human Concentration: ~1mg/ml Form: Purified antibody in PBS, 0.03% sodium azide. Purity: Purified Immunogen: Purified recombinant fragment of SNCG expressed in E. coli. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫组化免疫印迹

-20°C

1. Haiyan Liu, Wei Liu, Yinwei Wu. Cancer Res. 2005 Sep 1;65(17):7635-43. 2. Irina Surgucheva , Belinda McMahon , Andrei Surguchov. Cell Motil Cytoskeleton. 2006 May 26.