抗体

肿瘤坏死因子甲(肿瘤坏死因子)

030690

100微升

473美元

单克隆

小鼠

未共轭

13B768

肿瘤坏死因子甲(肿瘤坏死因子)

小鼠

单克隆抗体

抗体

100微升

473美元

13B768

IgG1

TNF-alpha (tumor necrosis factor alpha) is an important cytokine produced by numerous cell types including neutrophils, activated lymphocytes, macrophages and NK cells. It plays a critical role in inflammatory responses and in apoptosis. TNF-alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF-alpha exists as a multimer of two, three, or five non covalently linked units, but shows a single 17kD band following SDS PAGE under non reducing conditions. Although it has little effect on many cultured normal human cells, TNF-alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF-alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF-alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex. Applications: Western Bloting: 1:500-1:2000. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

DIF;TNFA;TNFSF2;肿瘤坏死因子甲

Recombinant protein corresponding to human TNF-alpha.

识别人类肿瘤坏死因子甲

腹水

Supplied as a liquid in 0.03% sodium azide.

未确定

Product Type: Mab Isotype: IgG1 Clone No: 13B768 Host: mouse Source: human Concentration: Not determined Form: Supplied as a liquid in 0.03% sodium azide. Purity: Ascites Immunogen: Recombinant protein corresponding to human TNF-alpha. Specificity: Recognizes human TNF-alpha. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫印迹

-20°C

1. Knowlton KU. Yajima T. J Am Coll Cardiol. 2004,Sep 15, 44(6):1298-300. 2. Reynolds JL. Ignatowski TA. Gallant S.et al. Brain Res. 2004,Oct 8, 1023(1):112-20. 3. Dulak J. Tomala K. Loboda A. et al. Life Sci. 2004,Oct 8, 75(21):2573-86.

https://usbio-images.r.worldssl.net/prodimages/33/030690_1.jpg