TNK1 (tyrosine kinase, non-receptor 1) | US Biological 030693 产品信息

产品简要

公司名称 :

US Biological

产品类型 :

抗体

产品名称 :

TNK1 (tyrosine kinase, non-receptor 1)

030693

规格 :

100微升

价格 :

436美元

克隆性 :

单克隆

宿主 :

小鼠

共轭标签 :

未共轭

克隆名称 :

13B771

反应物种 :

人类

更多信息或购买 :

US Biological 产品网页

产品信息

目录号 :

030693

Product wo Prefix :

TNK1 (tyrosine kinase, non-receptor 1)

宿主 :

小鼠

产品类型 :

单克隆抗体

类别 :

抗体

尺寸1 :

100微升

Size1 List :

436美元

克隆#USB :

13B771

抗体亚型 :

IgG1

Desc1 :

TNK1: tyrosine kinase, non-receptor, 1. TNK1 is a nonreceptor tyrosine kinase(NRPTK). These kinases, like members of the SRC (MIM 190090) and JAK (see MIM 147795) families, mediate intracellular signaling downstream of receptor activation.Tnk1 is a ubiquitously expressed 47kD protein with autotyrosine kinase activity that is developmentally regulated during embryogenesis. Tnk1 is also upregulated following IL3 withdrawal from factor-dependent murine NSF/N1.H7 cells that undergo apoptosis, suggesting a role in growth inhibition. Data support a negative regulatory role for Tnk1 in regulating the Ras-Raf1-MAPK growth pathway by a mechanism that requires its autotyrosine kinase activity. Applications: Western Bloting: 1:500-1:2000. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

又名 :

MGC46193;TNK1

免疫原 :

Purified recombinant fragment of TNK1 (aa451-560) expressed in E. coli.

特异性 :

人类

纯度 :

腹水

形式 :

Ascites fluid, 0.03% sodium azide.

浓度 :

未确定

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 13B771 Host: mouse Source: human Concentration: Not determined Form: Ascites fluid, 0.03% sodium azide. Purity: Ascites Immunogen: Purified recombinant fragment of TNK1 (aa451-560) expressed in E. coli. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E免疫印迹

储存温度 :

-20°C

参考文献 :

1. Oncogene. 1996 Feb 15;12(4):903-13. 2. Oncogene. 2003 Jun 5;22(23):3562-77. 3. Oncogene. 2007 Oct 4;26(45):6536-45.

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US Biological 产品网页

公司信息