抗体

肌动蛋白, 甲(ACTA1, ACTA, 骨骼肌, 阿尔法肌动蛋白)(生物素)

030740生物素

200微升

711美元

单克隆

小鼠

生物素

337CT30.10.1

肌动蛋白, 甲(ACTA1, ACTA, 骨骼肌, 阿尔法肌动蛋白)(生物素)

小鼠

单克隆抗体

生物素

抗体

200微升

711美元

337CT30.10.1

IgG1, k

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. Applications: Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry and ELISA. Other applications have not been tested. Recommended Dilution: Immunohistochemistry: Formalin-fixed, paraffin-embedded sections Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.

Hu

ACTA1, ACTA, 肌动蛋白, 甲骨骼肌, 阿尔法肌动蛋白

Recombinant protein corresponding to human Actin, alpha. Species Sequence Homology: bovine, chicken, mouse, procine, rabbit and rat

识别人类肌动蛋白, 甲

Purified by Protein G affinity chromatography.

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

As Reported

Product Type: Mab Isotype: IgG1,k Clone No: 337CT30.10.1 Host: mouse Source: human Concentration: As Reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin. Purity: Purified by Protein G affinity chromatography. Immunogen: Recombinant protein corresponding to human Actin, alpha. Species Sequence Homology: bovine, chicken, mouse, procine, rabbit and rat Specificity: Recognizes human Actin, alpha. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E FC免疫组化免疫印迹

-20°C

1. Kim, E.Y., et al. Am. J. Physiol. Renal Physiol. 299 (3), F594-F604 (2010) 2. Haigh, S.E., et al. Neuromuscul. Disord. 20(6):363-374(2010) 3. Yu, G., et al. J Clin Neurosci 17(6):766-769(2010) 4. Yu, C.H., et al. PLoS ONE 5 (7), E11878 (2010) 5. Licastro, F., et al. Curr. Pharm. Des. 16(7):783-788(2010)

https://usbio-images.r.worldssl.net/prodimages/26/030740-Biotin_1.jpg

Flow Cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram) using 030740. FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.