产品简要
公司名称 :
US Biological
产品类型 :
抗体
产品名称 :
Androgen Receptor Protein (AR, DHTR, NR3C4, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4)
目录 :
030771
规格 :
200微升
价格 :
569美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
549CT16.1。 4
反应物种 :
人类
更多信息或购买 :
产品信息
目录号 :
030771
Product wo Prefix :
Androgen Receptor Protein (AR, DHTR, NR3C4, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4)
宿主 :
小鼠
产品类型 :
单克隆抗体
类别 :
抗体
尺寸1 :
200微升
Size1 List :
569美元
克隆#USB :
549CT16.1。 4
抗体亚型 :
IgA
Desc1 :
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100~250 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Calc Crossreactivity :
Hu
又名 :
AR, DHTR, NR3C4, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4
免疫原 :
Purified His-tagged Androgen Receptor Protein (fragment).
特异性 :
人类
纯度 :
Purified by ammonium sulfate precipitation.
形式 :
以溶解在PBS液体方式提供, pH值7.2, 0.09% 叠氮化钠
浓度 :
As reported
Desc2 :
Product Type: Mab Isotype: IgA Clone No: 549CT16.1.4 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide. Purity: Purified by ammonium sulfate precipitation. Immunogen: Purified His-tagged Androgen Receptor Protein (fragment). Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E免疫印迹
储存温度 :
-20°C
参考文献 :
Shu, S.K., et al. J. Biol. Chem. 285(43):33045-33053(2010) Nedelsky, N.B., et al. Neuron 67(6):936-952(2010) Panda, B., et al. Gynecol. Endocrinol. (2010) In press Schneider, G., et al. Am J Geriatr Psychiatry (2010) In press Guadalupe-Grau, A., et al. PLoS ONE 5 (7), E11529 (2010)
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/33/030771_1.jpg
更多信息或购买 :
公司信息
US Biological
4 Technology Way
Salem, MA01970
tech@usbio.net
https://www.usbio.net
800-520-3011 781-639-5092
公司总部: 美国
United States Biological是生命科学领域的知名品牌,致力于用真实、有价值的个性化采购经验降低研究用成本。