抗体

CTNNB1, CT (CTNNB1, CTNNB, Catenin beta-1, Beta-catenin)

030898

100微升

569美元

单克隆

小鼠

未共轭

691CT11.2。 1

CTNNB1, CT (CTNNB1, CTNNB, Catenin beta-1, Beta-catenin)

小鼠

单克隆抗体

抗体

100微升

569美元

691CT11.2。 1

IgG1

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:500~4000 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Hu

CTNNB1, CTNNB, Catenin beta-1, Beta-catenin

CTNNB1 Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from human CTNNB1.

人类

腹水

Supplied as a liquid, crude ascites with 0.09% sodium azide.

As reported

Product Type: Mab Isotype: IgG1 Clone No: 691CT11.2.1 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid, crude ascites with 0.09% sodium azide. Purity: Ascites Immunogen: CTNNB1 Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from human CTNNB1. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫印迹

-20°C

Huang, W., et al. Mol. Cell. Biol. 30(19):4575-4594(2010) Chairoungdua, A., et al. J. Cell Biol. 190(6):1079-1091(2010) Mirza, M.K., et al. J. Exp. Med. 207(8):1675-1685(2010) Guo, Q., et al. Acta Biochim. Biophys. Sin. (Shanghai) 42(7):450-456(2010) Teng, Y., et al. Zhonghua Yi Xue Za Zhi 90(14):988-992(2010)

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