抗体

GSTA1 (GSTA1, Glutathione S-transferase A1, GST HA subunit 1, GST class-alpha member 1, GST-epsilon, GSTA1-1, GTH1)

031006

100微升

569美元

单克隆

小鼠

未共轭

286CT8.1。 5

GSTA1 (GSTA1, Glutathione S-transferase A1, GST HA subunit 1, GST class-alpha member 1, GST-epsilon, GSTA1-1, GTH1)

小鼠

单克隆抗体

抗体

100微升

569美元

286CT8.1。 5

IgM, k

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1000 Western Blot: 1:1000~32000 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Mo

GSTA1, Glutathione S-transferase A1, GST HA subunit 1, GST class-alpha member 1, GST-epsilon, GSTA1-1, GTH1

GSTA1 Mab is generated from mouse immunized with GSTA1 recombinant protein.

识别GSTA1

腹水

Supplied as a liquid, crude ascites with 0.09% sodium azide.

As reported

Product Type: Mab Isotype: IgM,k Clone No: 286CT8.1.5 Host: mouse Concentration: As reported Form: Supplied as a liquid, crude ascites with 0.09% sodium azide. Purity: Ascites Immunogen: GSTA1 Mab is generated from mouse immunized with GSTA1 recombinant protein. Specificity: Recognizes GSTA1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫印迹

-20°C

Elhasid, R., et al. Pediatr Blood Cancer 55(6):1172-1179(2010) Hawken, S.J., et al. Hum. Genet. 128(1):89-101(2010) Oguztuzun, S., et al. Folia Histochem. Cytobiol. 48(1):122-127(2010) Eriksen, K.T., et al. J. Toxicol. Environ. Health Part A 73(9):583-595(2010) Nguyen, T.V., et al. Oncol. Res. 18(7):349-355(2010)

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