抗体

NANOG (NANOG, Homeobox protein NANOG, Homeobox transcription factor Nanog)

031151

200微升

569美元

单克隆

小鼠

未共轭

60CT77.1。 1

NANOG (NANOG, Homeobox protein NANOG, Homeobox transcription factor Nanog)

小鼠

单克隆抗体

抗体

200微升

569美元

60CT77.1。 1

IgG1, k

Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes (By similarity). Acts as a transcriptional activator or repressor (By similarity). Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' (By similarity). When overexpressed, promotes cells to enter into S phase and proliferation (By similarity). Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA. Recommended Dilution: ELISA: 1:1000 Western Blot: 1:100~250 Immunohistochemistry: 1:10~50 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Hu

NANOG, Homeobox protein NANOG, Homeobox transcription factor Nanog

NANOG Mab is generated from mouse immunized with NANOG recombinant protein.

人类

Purified by Protein G affinity chromatography.

以溶解在PBS液体方式提供, pH值7.2, 0.09% 叠氮化钠

As reported

Product Type: Mab Isotype: IgG1,k Clone No: 60CT77.1.1 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide. Purity: Purified by Protein G affinity chromatography. Immunogen: NANOG Mab is generated from mouse immunized with NANOG recombinant protein. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫组化免疫印迹

-20°C

Trubiani, O., et al. J. Cell. Physiol. 225(1):123-131(2010) Po, A., et al. EMBO J. 29(15):2646-2658(2010) Zbinden, M., et al. EMBO J. 29(15):2659-2674(2010) Moretto-Zita, M., et al. Proc. Natl. Acad. Sci. U.S.A. 107(30):13312-13317(2010) Kuijk, E.W., et al. PLoS ONE 5 (6), E10987 (2010)

https://usbio-images.r.worldssl.net/prodimages/2/031151_1.jpg