抗体

Notch3, CT (Notch homolog 3, Drosophila, hN3, CASIL, CADASIL)

031161

100微升

569美元

单克隆

小鼠

未共轭

487CT6.9。 2

Notch3, CT (Notch homolog 3, Drosophila, hN3, CASIL, CADASIL)

小鼠

单克隆抗体

抗体

100微升

569美元

487CT6.9。 2

IgG1

This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq]. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100~1600 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Hu

NOTCH3 Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from the C-term region of human NOTCH3.

人类

腹水

Supplied as a liquid, crude ascites with 0.09% sodium azide.

As reported

Product Type: Mab Isotype: IgG1 Clone No: 487CT6.9.2 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid, crude ascites with 0.09% sodium azide. Purity: Ascites Immunogen: NOTCH3 Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from the C-term region of human NOTCH3. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫印迹

-20°C

Liu, H., et al. Circ. Res. 107(7):860-870(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Menon, S., et al. Cephalalgia (2010) In press Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010)

https://usbio-images.r.worldssl.net/prodimages/7/031161_1.jpg