抗体

Notch3, CT (Notch homolog 3, Drosophila, hN3, CASIL, CADASIL) (AP)

031162-AP

200微升

711美元

单克隆

小鼠

AP

487CT6.9。 2

Notch3, CT (Notch homolog 3, Drosophila, hN3, CASIL, CADASIL) (AP)

小鼠

单克隆抗体

AP

抗体

200微升

711美元

487CT6.9。 2

IgG1

This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq]. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100~250 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C with the addition of glycerol. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Do not freeze alkaline phosphatase conjugates which could result in a substantial loss of enzymatic activity. Light sensitive. Note: Applications are based on unconjugated antibody.

Hu

NOTCH3 Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from the C-term region of human NOTCH3.

人类

Purified by Protein G affinity chromatography.

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

As reported

Product Type: Mab Isotype: IgG1 Clone No: 487CT6.9.2 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein G affinity chromatography. Immunogen: NOTCH3 Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from the C-term region of human NOTCH3. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫印迹

4°C不冻结

Liu, H., et al. Circ. Res. 107(7):860-870(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Menon, S., et al. Cephalalgia (2010) In press Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010)

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