抗体

NPM (Nucleolar protein NO38, Numatrin, Nucleolar phosphoprotein B23, Nucleophosmin, NPM,Npm1) discontinued

031163

200微升

511美元

单克隆

小鼠

未共轭

3A9F1

NPM (Nucleolar protein NO38, Numatrin, Nucleolar phosphoprotein B23, Nucleophosmin, NPM,Npm1) discontinued

小鼠

单克隆抗体

抗体

200微升

511美元

3A9F1

IgG1

RNA-associated nucleolar phosphoprotein; involved in ribosome assembly [RGD] Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1000 Western Blot: 1:4~60 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Hu

Nucleolar protein NO38, Numatrin, Nucleolar phosphoprotein B23, Nucleophosmin, NPM,Npm1

Rat NPM antibody is generated from mouse immunized with Rat NPM recombinant protein.

人类

Purified by Protein G affinity chromatography.

以溶解在PBS液体方式提供, pH值7.2, 0.09% 叠氮化钠

As reported

Product Type: Mab Isotype: IgG1 Clone No: 3A9F1 Host: mouse Source: rat Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide. Purity: Purified by Protein G affinity chromatography. Immunogen: Rat NPM antibody is generated from mouse immunized with Rat NPM recombinant protein. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫印迹

-20°C

Protein B23/nucleophosmin/numatrin nuclear dynamics in relation to protein kinase CK2 and apoptotic activity in prostate cells. Wang G, et al. Biochemistry, 2010 May 11. PMID 20387789. Nucleophosmin may act as an alarmin: implications for severe sepsis. Nawa Y, et al. J Leukoc Biol, 2009 Sep. PMID 19581374. Disruption of ATP binding destabilizes NPM/B23 and inhibits anti-apoptotic function. Choi JW, et al. BMB Rep, 2008 Dec 31. PMID 19123973. Nuclear Akt interacts with B23/NPM and protects it from proteolytic cleavage, enhancing cell survival. Lee SB, et al. Proc Natl Acad Sci U S A, 2008 Oct 28. PMID 18931307. Ebp1 association with nucleophosmin/B23 is essential for regulating cell proliferation and suppressing apoptosis. Okada M, et al. J Biol Chem, 2007 Dec 14. PMID 17951246.