抗体

RET (RET, CDHF12, CDHR16, PTC, RET51, Proto-oncogene tyrosine-protein kinase receptor Ret, Cadherin family member 12, Proto-oncogene c-Ret, Soluble RET kinase fragment, Extracellular cell-membrane anchored RET cadherin 120kD fragment)

031219

100微升

511美元

单克隆

小鼠

未共轭

188CT11.2。 3

RET (RET, CDHF12, CDHR16, PTC, RET51, Proto-oncogene tyrosine-protein kinase receptor Ret, Cadherin family member 12, Proto-oncogene c-Ret, Soluble RET kinase fragment, Extracellular cell-membrane anchored RET cadherin 120kD fragment)

www.usbio.net/antibodies/031219/RET-RET-CDHF12-CDHR16-PTC-RET51-Protooncogene-tyrosineprotein-kinase-receptor-Ret-Cadherin-family-member-12-Protooncogene-cRet-Soluble-RET-kinase-fragment-Extracellular-cellmembrane-anchored-RET-cadherin-120kD-fragment

小鼠

单克隆抗体

抗体

100微升

511美元

188CT11.2。 3

IgM, k

This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. Applications:. Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, ELISA. Recommended Dilution:. ELISA: 1:1000. Western Blot: 1:500~16000. Immunohistochemistry: 1:50~100. Immunofluorescence: 1:10~50. Storage and Stability:. May be stored at 4 C for short-term only. For long-term storage, store at -20 C. Aliquots are stable for at least 12 months at -20 C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Hu

RET, CDHF12, CDHR16, PTC, RET51, Proto-oncogene tyrosine-protein kinase receptor Ret, Cadherin family member 12, Proto-oncogene c-Ret, Soluble RET kinase fragment, Extracellular cell-membrane anchored RET cadherin 120kD fragment

RET Mab was raised using purified His-tagged recombinant human RET.

人类

腹水

Supplied as a liquid, crude ascites with 0.09% sodium azide.

As reported

Product Type: Mab. Isotype: IgM,k. Clone No: 188CT11.2.3. Host: mouse. Source: human. Concentration: As reported. Form: Supplied as a liquid, crude ascites with 0.09% sodium azide. Purity: Ascites. Immunogen: RET Mab was raised using purified His-tagged recombinant human RET. Specificity: Human. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E IF免疫组化免疫印迹

-20 C

Siqueira, D.R., et al. Endocr. Relat. Cancer 17(4):953-963(2010). Gockel, H.R., et al. Hum. Genet. 128(4):353-364(2010). Kim, H.K., et al. Anticancer Res. 30(9):3621-3627(2010). Pacini, F., et al. Clin Oncol (R Coll Radiol) 22(6):475-485(2010). Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010)

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