抗体

TIMP1 (TIMP1, CLGI, TIMP, Metalloproteinase inhibitor 1, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, Tissue inhibitor of metalloproteinases 1)

031291

200微升

569美元

单克隆

小鼠

未共轭

3F10F14

TIMP1 (TIMP1, CLGI, TIMP, Metalloproteinase inhibitor 1, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, Tissue inhibitor of metalloproteinases 1)

小鼠

单克隆抗体

抗体

200微升

569美元

3F10F14

IgG1, k

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. Applications: Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:100-1:250 Immunofluorescence: 1:10-1:50 Immunohistochemistry (FFPE): 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

TIMP1, CLGI, TIMP, Metalloproteinase inhibitor 1, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, Tissue inhibitor of metalloproteinases 1

Recombinant protein corresponding to human TIMP1

识别人类TIMP1

Purified by Protein G affinity chromatography.

以溶解在PBS液体方式提供, pH值7.2, 0.09% 叠氮化钠

As reported

Product Type: Mab Isotype: IgG1,k Clone No: 3F10F14 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein G affinity chromatography. Immunogen: Recombinant protein corresponding to human TIMP1 Specificity: Recognizes human TIMP1. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E IF免疫组化免疫印迹

-20°C

1. Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) 2. Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) 3. Lin, C.C., et al. Clin J Am Soc Nephrol 5(10):1805-1814(2010) 4. Yeh, Y.C., et al. BMC Microbiol. 10, 218 (2010) 5. Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010)