抗体

Toll样受体3(Toll样受体3, Toll样受体3, CD_antigen=CD283)

031296

100微升

569美元

单克隆

小鼠

未共轭

303CT19.9。 2

Toll样受体3(Toll样受体3, Toll样受体3, CD_antigen=CD283)

小鼠

单克隆抗体

抗体

100微升

569美元

303CT19.9。 2

IgM

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1000 Western Blot: 1:100~4000 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Mo

TLR3, Toll-like receptor 3, CD_antigen=CD283, Flags: Precursor

TLR3 Mab is generated from mouse immunized with TLR3 recombinant protein.

小鼠

腹水

Supplied as a liquid, crude ascites with 0.09% sodium azide.

As reported

Product Type: Mab Isotype: IgM Clone No: 303CT19.9.2 Host: mouse Source: mouse Concentration: As reported Form: Supplied as a liquid, crude ascites with 0.09% sodium azide. Purity: Ascites Immunogen: TLR3 Mab is generated from mouse immunized with TLR3 recombinant protein. Specificity: Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫印迹

-20°C

Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) Perez de Diego, R., et al. Immunity 33(3):400-411(2010) Zhou, Y., et al. Immunology 131(1):40-49(2010) Perrot, I., et al. J. Immunol. 185(4):2080-2088(2010) Paone, A., et al. Neoplasia 12(7):539-549(2010)

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