抗体

肌动蛋白, alpha1, CT(ACTA1, ACTA, 肌动蛋白, 甲骨骼肌, 阿尔法肌动蛋白)(AP)

031572-AP

200微升

711美元

多克隆

domestic rabbit

AP

肌动蛋白, alpha1, CT(ACTA1, ACTA, 肌动蛋白, 甲骨骼肌, 阿尔法肌动蛋白)(AP)

兔

多克隆抗体

AP

抗体

200微升

711美元

IgG

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. Applications: Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry: Formalin-fixed, paraffin-embedded sections Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Hu

ACTA1, ACTA, 肌动蛋白, 甲骨骼肌, 阿尔法肌动蛋白

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 346-375 in the C-terminal region of human Actin, alpha1. Species Sequence Homology: bovine, chicken, mouse, porcine, rat, rabbit and Xenopus

识别人类肌动蛋白, alpha1

Purified by Protein A and peptide affinity chromatography.

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

As Reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As Reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 346-375 in the C-terminal region of human Actin, alpha1. Species Sequence Homology: bovine, chicken, mouse, porcine, rat, rabbit and Xenopus Specificity: Recognizes human Actin, alpha1. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫组化免疫印迹

4°C不冻结

1. Kim, E.Y., et al. Am. J. Physiol. Renal Physiol. 299 (3), F594-F604 (2010). 2. Haigh, S.E., et al. Neuromuscul. Disord. 20(6):363-374(2010). 3. Yu, G., et al. J Clin Neurosci 7(6):766-769(2010). 4. Yu, C.H., et al. PLoS ONE 5 (7), E11878 (2010). 5. Licastro, F., et al. Curr. Pharm. Des. 16(7):783-788(2010)

https://usbio-images.r.worldssl.net/prodimages/39/031572-AP_1.jpg