抗体

Activin Receptor Type IA, ID (R147) (ACVR1, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase 2, Serine/threonine-protein kinase receptor R1, TGF-B superfamily receptor type I)

031575

200微升

569美元

多克隆

domestic rabbit

未共轭

Activin Receptor Type IA, ID (R147) (ACVR1, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase 2, Serine/threonine-protein kinase receptor R1, TGF-B superfamily receptor type I)

兔

多克隆抗体

抗体

200微升

569美元

IgG

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. ACVR1 (activin A type I receptor) signals a particular transcriptional response in concert with activin type II receptors. Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu Mo

ACVR1, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase 2, Serine/threonine-protein kinase receptor R1, TGF-B superfamily receptor type I

ACVR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140~169 amino acids from the center region of human ACVR1.

人类, 小鼠

Purified by Protein G affinity chromatography.

以溶解在PBS液体方式提供, pH值7.2, 0.09% 叠氮化钠

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein G affinity chromatography. Immunogen: ACVR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140~169 amino acids from the center region of human ACVR1. Specificity: Human, mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫组化免疫印迹

-20°C

Schneider-Kolsky, M.E., et al., Placenta 23(4):294-302 (2002). Roijer, E., et al., Mamm. Genome 9(3):266-268 (1998). Attisano, L., et al., Cell 75(4):671-680 (1993). ten Dijke, P., et al., Oncogene 8(10):2879-2887 (1993). Matsuzaki, K., et al., J. Biol. Chem. 268(17):12719-12723 (1993).

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