产品简要
公司名称 :
US Biological
产品类型 :
抗体
产品名称 :
AKT1, phosphorylated (T450) (AKT1, PKB, RAC, RAC-alpha serine/threonine-protein kinase, Protein kinase B, Protein kinase B alpha, Proto-oncogene c-Akt, RAC-PK-alpha) (AP)
目录 :
031755-AP
规格 :
200微升
价格 :
711美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
AP
抗原修饰 :
磷酸化
反应物种 :
人类
更多信息或购买 :
产品信息
目录号 :
031755-AP
Product wo Prefix :
AKT1, phosphorylated (T450) (AKT1, PKB, RAC, RAC-alpha serine/threonine-protein kinase, Protein kinase B, Protein kinase B alpha, Proto-oncogene c-Akt, RAC-PK-alpha) (AP)
宿主 :
兔
产品类型 :
多克隆抗体
共轭标签 :
AP
抗原修饰 :
磷酸化
类别 :
抗体
尺寸1 :
200微升
Size1 List :
711美元
抗体亚型 :
IgG
Desc1 :
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].
Applications:
Suitable for use in Dot Blot, ELISA
Recommended Dilution:
ELISA: 1:1,000
Dot blot 1:100-500
Storage and Stability:
Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Calc Crossreactivity :
Hu
又名 :
AKT1, PKB, RAC, RAC-alpha serine/threonine-protein kinase, Protein kinase B, Protein kinase B alpha, Proto-oncogene c-Akt, RAC-PK-alpha
免疫原 :
KLH-conjugated synthetic phosphopeptide mapping to a fragment of residues surrounding T450 of human AKT1, UniProt Accession #P31749. Species Sequence Homology: bovine, mouse and rat
特异性 :
识别人类AKT1
纯度 :
Purified by Protein A affinity chromatography.
形式 :
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
浓度 :
As Reported
Desc2 :
Product Type: Pab
Isotype: IgG
Host: rabbit
Source: human
Concentration: As Reported
Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Purity: Purified by Protein A affinity chromatography.
Immunogen: KLH-conjugated synthetic phosphopeptide mapping to a fragment of residues surrounding T450 of human AKT1, UniProt Accession #P31749. Species Sequence Homology: bovine, mouse and rat
Specificity: Recognizes human AKT1.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
DB E
储存温度 :
4°C不冻结
参考文献 :
1. Zhao, W.D., et al. Infect. Immun. 78(11):4809-4816(2010). 2. Sanematsu, F., et al. Circ. Res. 107(9):1102-1105(2010). 3. Nicodemus, K.K., et al. Arch. Gen. Psychiatry 67(10):991-1001(2010). 4. Treekitkarnmongkol, W., et al. World J. Gastroenterol. 16(32):4047-4054(2010). 5. Chen, J., et al. PLoS ONE 5 (8), E12293 (2010)
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/5/031755-AP_1.jpg
更多信息或购买 :
公司信息
US Biological
4 Technology Way
Salem, MA01970
Salem, MA01970
tech@usbio.net
https://www.usbio.net800-520-3011 781-639-5092
公司总部: 美国
United States Biological是生命科学领域的知名品牌,致力于用真实、有价值的个性化采购经验降低研究用成本。
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