产品简要
公司名称 :
US Biological
产品类型 :
抗体
产品名称 :
CD130, CT (IL6ST, Interleukin-6 receptor subunit beta, CDw130, Interleukin-6 signal transducer, Membrane glycoprotein 130, Oncostatin-M receptor subunit alpha, CD130) (AP)
目录 :
033450-AP
规格 :
200微升
价格 :
711美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
AP
反应物种 :
人类
更多信息或购买 :
产品信息
目录号 :
033450-AP
Product wo Prefix :
CD130, CT (IL6ST, Interleukin-6 receptor subunit beta, CDw130, Interleukin-6 signal transducer, Membrane glycoprotein 130, Oncostatin-M receptor subunit alpha, CD130) (AP)
宿主 :
产品类型 :
多克隆抗体
共轭标签 :
AP
类别 :
抗体
尺寸1 :
200微升
Size1 List :
711美元
抗体亚型 :
IgG
Desc1 :
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated Herpes virus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17. Applications: Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications have not been tested. Recommended Dilution: Immunohistochemistry: Formalin-fixed, paraffin-embedded sections Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
Calc Crossreactivity :
Hu
又名 :
IL6ST, Interleukin-6 receptor subunit beta, CDw130, Interleukin-6 signal transducer, Membrane glycoprotein 130, Oncostatin-M receptor subunit alpha, CD130
免疫原 :
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 871-899 in the C-terminal region of human CD130.
特异性 :
识别人类CD130
纯度 :
Purified by Protein A and peptide affinity chromatography.
形式 :
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
浓度 :
As reported
Desc2 :
Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 871-899 in the C-terminal region of human CD130. Specificity: Recognizes human CD130. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E免疫组化免疫印迹
储存温度 :
4°C不冻结
参考文献 :
1. Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) 2. Goette, N.P., et al. Exp. Hematol. 38(10):868-876(2010) 3. Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) : 4. Olsen, J.V., et al. Cell 127(3):635-648(2006) 5. Richards, P.J., et al. Arthritis Rheum. 54(5):1662-1672(2006)
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/19/033450-AP_1.jpg
Picture4文本 :
Staining CD130 in Human skeletal muscle tissue sections by Immunohistochemistry (FFPE) using 033450. Tissue was fixed with formaldehyde and blocked with 3% BSA for 0.5 hour at RT; antigen retrieval was by heat mediation with a citrate buffer (pH6). Samples were incubated with 033450 (1:25) for 1 hours at 37°C. A undiluted biotinylated goat polyvalent antibody was used as the secondary antibody.
Picture 5 File Name :
https://usbio-images.r.worldssl.net/prodimages/19/033450-AP_5.jpg
Picture5文本 :
Immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue using 033450 followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of 033450 for immunohistochemistry. Clinical relevance has not been evaluated.
更多信息或购买 :
公司信息
US Biological
4 Technology Way
Salem, MA01970
tech@usbio.net
https://www.usbio.net
800-520-3011 781-639-5092
公司总部: 美国
United States Biological是生命科学领域的知名品牌,致力于用真实、有价值的个性化采购经验降低研究用成本。