产品简要
公司名称 :
US Biological
产品类型 :
抗体
产品名称 :
CD31, CT (Pecam1, Pecam, Pecam-1, Platelet endothelial cell adhesion molecule, CD31) (AP)
目录 :
033493-AP
规格 :
200微升
价格 :
711美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
AP
反应物种 :
小鼠
更多信息或购买 :
产品信息
目录号 :
033493-AP
Product wo Prefix :
CD31, CT (Pecam1, Pecam, Pecam-1, Platelet endothelial cell adhesion molecule, CD31) (AP)
宿主 :
产品类型 :
多克隆抗体
共轭标签 :
AP
类别 :
抗体
尺寸1 :
200微升
Size1 List :
711美元
抗体亚型 :
IgG
Desc1 :
Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-679 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. During apoptosis, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore. The lack of this repulsion signal together with the interaction of the eat-me signals and their respective receptors causes the attachment of the apoptotic cell to the phagocyte, thus triggering the process of engulfment). Modulates BDKRB2 activation (By similarity). Induces susceptibility to atherosclerosis. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
Calc Crossreactivity :
Hm Mo
又名 :
Pecam1, Pecam, Pecam-1, Platelet endothelial cell adhesion molecule, CD31
免疫原 :
Mouse CD31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 511-540 amino acids from the C-terminal region of human Mouse CD31.
特异性 :
仓鼠, 小鼠
纯度 :
Purified by Protein A affinity chromatography.
形式 :
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
浓度 :
As reported
Desc2 :
Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A affinity chromatography. Immunogen: Mouse CD31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 511-540 amino acids from the C-terminal region of human Mouse CD31. Specificity: Hamster, mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E免疫印迹
储存温度 :
4°C不冻结
参考文献 :
DeLisser, H., et al. Proc. Natl. Acad. Sci. U.S.A. 107(43):18616-18621(2010) Zhang, C., et al. Dev. Dyn. 239(10):2594-2602(2010) Enciso, J.M., et al. Dev. Dyn. 239(10):2570-2583(2010) Ni, A., et al. Dev. Dyn. 239(9):2354-2366(2010) Sessa, A., et al. Genes Dev. 24(16):1816-1826(2010)
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/7/033493-AP_1.jpg
更多信息或购买 :
公司信息
US Biological
4 Technology Way
Salem, MA01970
tech@usbio.net
https://www.usbio.net
800-520-3011 781-639-5092
公司总部: 美国
United States Biological是生命科学领域的知名品牌,致力于用真实、有价值的个性化采购经验降低研究用成本。