抗体

CD3E, CT (CD3E, T3E, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e)

033502

200微升

569美元

多克隆

domestic rabbit

未共轭

CD3E, CT (CD3E, T3E, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e)

兔

多克隆抗体

抗体

200微升

569美元

IgG

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

CD3E, T3E, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 154-182 in the C-terminal region of human CD3E, UniProt Accession #NP_000724.1; P07766; Q95LI5. Species sequence homology: monkey

识别人类CD3E

Purified by Protein A and peptide affinity chromatography.

以溶解在PBS液体方式提供, pH值7.2, 0.09% 叠氮化钠

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 154-182 in the C-terminal region of human CD3E, UniProt Accession #NP_000724.1; P07766; Q95LI5. Species sequence homology: monkey Specificity: Recognizes human CD3E. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫印迹

-20°C

1. Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) 2. Davila, S., et al. Genes Immun. 11(3):232-238(2010) 3. Brophy, K., et al. BMC Med. Genet. 11, 76 (2010) 4. Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) 5. Su, Z., et al. Int. J. Mol. Med. 24(4):437-444(2009)

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