抗体

CD40, CT (CD40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, B Cell surface antigen CD40, Bp50, CD40L receptor, CDw40, CD40)

033512

200微升

569美元

多克隆

domestic rabbit

未共轭

CD40, CT (CD40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, B Cell surface antigen CD40, Bp50, CD40L receptor, CDw40, CD40)

兔

多克隆抗体

抗体

200微升

569美元

IgG

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

CD40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, CDw40, CD40

CD40 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-276 amino acids from the C-terminal region of human CD40.

人类

Purified by Protein A affinity chromatography.

以溶解在PBS液体方式提供, pH值7.2, 0.09% 叠氮化钠

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: CD40 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-276 amino acids from the C-terminal region of human CD40. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫印迹

-20°C

Rodriguez-Rodriguez, L., et al. J. Rheumatol. 37(10):2076-2080(2010) Lewis, J.P., et al. Genomics 96(4):211-219(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Blanco-Kelly, F., et al. PLoS ONE 5 (7), E11520 (2010) : Soliman, M.A., et al. Egypt J Immunol 16(1):61-70(2009)

https://usbio-images.r.worldssl.net/prodimages/10/033512_1.jpg