抗体

DSG1, ID (DSG1, CDHF4, Desmoglein-1, Cadherin family member 4, Desmosomal glycoprotein 1, Pemphigus foliaceus antigen)

034827

200微升

569美元

多克隆

domestic rabbit

未共轭

DSG1, ID (DSG1, CDHF4, Desmoglein-1, Cadherin family member 4, Desmosomal glycoprotein 1, Pemphigus foliaceus antigen)

兔

多克隆抗体

抗体

200微升

569美元

IgG

Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus. Applications: Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications have not been tested. Recommended Dilutions: Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

DSG1, CDHF4, Desmoglein-1, Cadherin family member 4, Desmosomal glycoprotein 1, Pemphigus foliaceus antigen

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 471-499 in the central region of human DSG1, UniProt Accession #Q02413.

识别人类DSG1

Purified by Protein A affinity chromatography.

以溶解在PBS液体方式提供, pH值7.2, 0.09% 叠氮化钠

As Reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As Reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 471-499 in the central region of human DSG1, UniProt Accession #Q02413. Specificity: Recognizes human DSG1. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫组化免疫印迹

-20°C

1. Rothenberg, M.E., et al. Nat. Genet. 42(4):289-291(2010). 2. Naoe, Y., et al. J. Dermatol. Sci. 57(3):192-198(2010). 3. Qian, Y., et al. J. Invest. Dermatol. 129(12):2823-2834(2009). 4. Spindler, V., et al. J. Biol. Chem. 284(44):30556-30564(2009). 5. Getsios, S., et al. J. Cell Biol. 185(7):1243-1258(2009)

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