产品简要
公司名称 :
US Biological
产品类型 :
抗体
产品名称 :
HLA-B, ID (HLA-B, HLAB, HLA class I histocompatibility antigen, B-7 alpha chain, MHC class I antigen B*7) (AP)
目录 :
036616-AP
规格 :
200微升
价格 :
711美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
AP
反应物种 :
人类
更多信息或购买 :
产品信息
目录号 :
036616-AP
Product wo Prefix :
HLA-B, ID (HLA-B, HLAB, HLA class I histocompatibility antigen, B-7 alpha chain, MHC class I antigen B*7) (AP)
宿主 :
兔
产品类型 :
多克隆抗体
共轭标签 :
AP
类别 :
抗体
尺寸1 :
200微升
Size1 List :
711美元
抗体亚型 :
IgG
Desc1 :
HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.
Applications:
Suitable for use in Western Blot, ELISA
Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500
Storage and Stability:
Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Calc Crossreactivity :
Hu
又名 :
HLA-B, HLAB, HLA class I histocompatibility antigen, B-7 alpha chain, MHC class I antigen B*7
免疫原 :
HLA-B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184-212 amino acids from the Central region of human HLA-B.
特异性 :
人类
纯度 :
Purified by Protein A affinity chromatography.
形式 :
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
浓度 :
As reported
Desc2 :
Product Type: Pab
Isotype: IgG
Host: rabbit
Source: human
Concentration: As reported
Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Purity: Purified by Protein A affinity chromatography.
Immunogen: HLA-B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184-212 amino acids from the Central region of human HLA-B.
Specificity: Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E免疫印迹
储存温度 :
4°C不冻结
参考文献 :
Parsons, M.S., et al. J. Infect. Dis. 202 SUPPL 3, S356-S360 (2010) :
Brockman, M.A., et al. J. Virol. 84(22):11937-11949(2010)
Noble, J.A., et al. Diabetes 59(11):2972-2979(2010)
Lipponen, K., et al. Diabetes (2010) In press :
Liao, Y.Q., et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi 18(4):1055-1058(2010)
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/2/036616-AP_1.jpg
更多信息或购买 :
公司信息
US Biological
4 Technology Way
Salem, MA01970
Salem, MA01970
tech@usbio.net
https://www.usbio.net800-520-3011 781-639-5092
公司总部: 美国
United States Biological是生命科学领域的知名品牌,致力于用真实、有价值的个性化采购经验降低研究用成本。
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