抗体

Il12b, ID (Il12b, Interleukin-12 subunit beta, Cytotoxic lymphocyte maturation factor 40kD subunit, IL-12 subunit p40)

036972

200微升

569美元

多克隆

domestic rabbit

未共轭

Il12b, ID (Il12b, Interleukin-12 subunit beta, Cytotoxic lymphocyte maturation factor 40kD subunit, IL-12 subunit p40)

兔

多克隆抗体

抗体

200微升

569美元

IgG

Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC (By similarity). Associates with IL23A to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. Applications: Suitable for use in Western Blot and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Mo

Il12b, Interleukin-12 subunit beta, Cytotoxic lymphocyte maturation factor 40kD subunit, IL-12 subunit p40

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 196-222 in the central region of mouse Il12b.

识别小鼠Il12b

Purified by Protein A and peptide affinity chromatography.

以溶解在PBS液体方式提供, pH值7.2, 0.09% 叠氮化钠

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: mouse Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 196-222 in the central region of mouse Il12b. Specificity: Recognizes mouse Il12b. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫印迹

-20°C

1. Kagami, S., et al. J. Immunol. 185(9):5453-5462(2010) 2. Wozniak, T.M., et al. Infect. Immun. 78(10):4187-4194(2010) 3. Lindsay, R.W., et al. J. Immunol. 185(3):1513-1521(2010) 4. Marshall, H.D., et al. J. Immunol. 185(3):1419-1428(2010) 5. Park, Y., et al. J. Immunol. 185(3):1476-1484(2010)

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