抗体

KDR (Y1175) (KDR, FLK1, VEGFR2, Vascular endothelial growth factor receptor 2, Fetal liver kinase 1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1)

037374

200微升

569美元

多克隆

domestic rabbit

未共轭

KDR (Y1175) (KDR, FLK1, VEGFR2, Vascular endothelial growth factor receptor 2, Fetal liver kinase 1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1)

兔

多克隆抗体

抗体

200微升

569美元

IgG

KDR is a major growth factor for endothelial cells. This protein encodes one of the two receptors of the KDR. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Applications: Suitable for use in Western Blot, Flow Cytometry and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:1000 Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu Mo

KDR, FLK1, VEGFR2, Vascular endothelial growth factor receptor 2, Fetal liver kinase 1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1153-1182 of human KDR, UniProt Accession #P35968.

Recognizes human KDR. Species crossreactivity: mouse

Purified by Protein A and peptide affinity chromatography.

以溶解在PBS液体方式提供, pH值7.2, 0.09% 叠氮化钠

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1153-1182 of human KDR, UniProt Accession #P35968. Specificity: Recognizes human KDR. Species crossreactivity: mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E FC免疫印迹

-20°C

Huang, D., et al. Cancer Res. 70(3):1053-1062(2010) Sentilhes, L., et al. J. Neuropathol. Exp. Neurol. 69(2):111-128(2010) Lamalice, L., et al. J. Biol. Chem. 281(45):34009-34020(2006) Meyer, R.D., et al. J. Biol. Chem. 277(30):27081-27087(2002)

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