产品简要
公司名称 :
US Biological
产品类型 :
抗体
产品名称 :
MLF1, CT (MLF1, Myeloid leukemia factor 1, Myelodysplasia-myeloid leukemia factor 1) (APC)
目录 :
038463-APC
规格 :
200微升
价格 :
711美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
APC
反应物种 :
人类
更多信息或购买 :
产品信息
目录号 :
038463-APC
Product wo Prefix :
MLF1, CT (MLF1, Myeloid leukemia factor 1, Myelodysplasia-myeloid leukemia factor 1) (APC)
宿主 :
产品类型 :
多克隆抗体
共轭标签 :
APC
类别 :
抗体
尺寸1 :
200微升
Size1 List :
711美元
抗体亚型 :
IgG
Desc1 :
MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus. Applications: Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry and FLISA. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry: Formalin fixed and paraffin embedded tissues Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
Calc Crossreactivity :
Hu Mo
又名 :
MLF1, Myeloid leukemia factor 1, Myelodysplasia-myeloid leukemia factor 1
免疫原 :
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 215-244 in the C-terminal region of human MLF1, UniProt Accession #P58340.
特异性 :
Recognizes human MLF1. Species Crossreactivity: mouse
纯度 :
Purified by Protein A and peptide affinity chromatography.
形式 :
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
浓度 :
As Reported
Desc2 :
Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As Reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC). Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 215-244 in the C-terminal region of human MLF1, UniProt Accession #P58340. Specificity: Recognizes human MLF1. Species Crossreactivity: mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
FC FL免疫组化免疫印迹
储存温度 :
4°C不冻结
参考文献 :
1. Li,Z.F., J. Neurol. Sci. 264 (1-2), 77-86 (2008) 2. Yoneda-Kato,N., EMBO J. 24 (9), 1739-1749 (2005)
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/27/038463-APC_1.pdf
Picture4文本 :
immunohistochemistry analysis of formalin fixed and paraffin embedded human testis tissue using 038463 followed by peroxidase conjugation of the secondary antibody and DAB staining.
Picture 5 File Name :
https://usbio-images.r.worldssl.net/prodimages/27/038463-APC_5.pdf
Picture5文本 :
Flow Cytometric analysis of CEM cells (bottom histogram) using 038463 compared to a negative control cell (top histogram) . FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
更多信息或购买 :
公司信息
US Biological
4 Technology Way
Salem, MA01970
tech@usbio.net
https://www.usbio.net
800-520-3011 781-639-5092
公司总部: 美国
United States Biological是生命科学领域的知名品牌,致力于用真实、有价值的个性化采购经验降低研究用成本。