产品简要
公司名称 :
US Biological
产品类型 :
抗体
产品名称 :
MYBPC3, NT (MYBPC3, Myosin-binding protein C, cardiac-type, C-protein, cardiac muscle isoform) (AP)
目录 :
038715-AP
规格 :
200微升
价格 :
711美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
AP
反应物种 :
人类
更多信息或购买 :
产品信息
目录号 :
038715-AP
Product wo Prefix :
MYBPC3, NT (MYBPC3, Myosin-binding protein C, cardiac-type, C-protein, cardiac muscle isoform) (AP)
宿主 :
产品类型 :
多克隆抗体
共轭标签 :
AP
类别 :
抗体
尺寸1 :
200微升
Size1 List :
711美元
抗体亚型 :
IgG
Desc1 :
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. Applications: Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications have not been tested. Recommended Dilution: Immunohistochemistry: Formalin-fixed, paraffin-embedded sections Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
Calc Crossreactivity :
Hu Mo Rt
又名 :
MYBPC3, Myosin-binding protein C, cardiac-type, C-protein, cardiac muscle isoform
免疫原 :
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 189-218 in the N-terminal region of human MYBPC3. Swiss/UniProt Accession: Q14896.
特异性 :
Recognizes human MYBPC3. Species Crossreactivity: mouse, rat
纯度 :
Purified by Protein A and peptide affinity chromatography.
形式 :
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
浓度 :
As reported
Desc2 :
Product Type: Pab Isotype: IgG Host: rabbit Source: mouse Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 189-218 in the N-terminal region of human MYBPC3. Swiss/UniProt Accession: Q14896. Specificity: Recognizes human MYBPC3. Species Crossreactivity: mouse, rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E免疫组化免疫印迹
储存温度 :
4°C不冻结
参考文献 :
1. Millat, G., et al. Clin. Chim. Acta 411 (23-24), 1983-1991 (2010) : 2. Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) 3. Millat, G., et al. Eur J Med Genet 53(5):261-267(2010) 4. Zimmerman, R.S., et al. Genet. Med. 12(5):268-278(2010) 5. Brion, M., et al. Ann. Clin. Lab. Sci. 40(3):285-289(2010)
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/6/038715-AP_1.png
Picture4文本 :
Immunohistochemistry of MYBPC3 in paraformaldehyde-fixed, paraffin-embedded sections of human heart tissue sections using 038715. Tissue was fixed with formaldehyde and blocked with 3% BSA for 0.5hrs at RT; antigen retrieval was by heat mediation with a citrate buffer (pH 6). Samples were incubated with 038715 (1:25) for 1hr at 37°C. A undiluted biotinylated goat polyvalent antibody was used as the secondary antibody.
更多信息或购买 :
公司信息
US Biological
4 Technology Way
Salem, MA01970
tech@usbio.net
https://www.usbio.net
800-520-3011 781-639-5092
公司总部: 美国
United States Biological是生命科学领域的知名品牌,致力于用真实、有价值的个性化采购经验降低研究用成本。