抗体

Myc, 磷酸化(pS62)(c-Myc, 转录因子p64)

038719

200微升

569美元

多克隆

domestic rabbit

未共轭

磷酸化

Myc, 磷酸化(pS62)(c-Myc, 转录因子p64)

兔

多克隆抗体

磷酸化

抗体

200微升

569美元

IgG

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. Applications: Suitable for use in Dot Blot, ELISA Recommended Dilution: ELISA1:1,000 Dot blot 1:500 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

c-Myc, 转录因子p64

Phospho-MYC-pS62 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S62 of human MYC.

人类

Purified by peptide immunoaffinity chromatography.

以溶解在PBS液体方式提供, pH值7.2, 0.09% 叠氮化钠

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by peptide immunoaffinity chromatography. Immunogen: Phospho-MYC-pS62 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S62 of human MYC. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

DB E

-20°C

Coller,H.A., PLoS Genet. 3 (8), E146 (2007) Zippo,A., Nat. Cell Biol. 9 (8), 932-944 (2007) Dai,M.S., EMBO J. 26 (14), 3332-3345 (2007) Yuneva,M., J. Cell Biol. 178 (1), 93-105 (2007)